Science Archives

Hockey Stick Graph Taken Out For a Penalty

Anthony Watts calls attention to a new study on the famed/infamous "hockey stick" graph purporting to show a huge uptick in global temperatures in the 20th century.

There is a new and important study on temperature proxy reconstructions (McShane and Wyner 2010) submitted into the Annals of Applied Statistics and is listed to be published in the next issue. According to Steve McIntyre, this is one of the “top statistical journals”. This paper is a direct and serious rebuttal to the proxy reconstructions of Mann.

Proxies are things like tree rings and ice core measurements, rather than actual thermometer readings.  From the paper’s abstract:

We find that the proxies do not predict temperature significantly better than random series generated independently of temperature. Furthermore, various model specifications that perform similarly at predicting temperature produce extremely different historical backcasts. Finally, the proxies seem unable to forecast the high levels of and sharp run-up in temperature in the 1990s either in-sample or from contiguous holdout blocks, thus casting doubt on their ability to predict such phenomena if in fact they occurred several hundred years ago.

The first sentence says essentially that proxy data does not predict future temperatures any better than picking temperature numbers at random. 

Wow.

I imagine this study will get a good looking-over by those on both sides of the issue, but if it stands scrutiny it would be a huge blow to the anthropogenic global warming theory.  Stay tuned.

Stem Cells From Blood Coming Soon?

It could happen.

Blood drawn with a simple needle stick can be coaxed into producing stem cells that may have the ability to form any type of tissue in the body, three independent papers report in the July 2 Cell Stem Cell. The new technique will allow scientists to tap a large, readily available source of personalized stem cells.

Because taking blood is safe, fast and efficient compared to current stem cell harvesting methods, some of which include biopsies and pretreatments with drugs, researchers hope that blood-derived stem cells could one day be used to study and treat diseases — though major safety hurdles remain.

The findings “represent a huge and important progression in the field,” stem cell biologist Shinya Yamanaka of Kyoto University in Japan and the Gladstone Institute of Cardiovascular Disease in San Francisco, Calif., writes in a commentary appearing in the same issue of the journal.

All this without the need to destroy embryos.  This just keep looking better and better for getting stem cells from adults rather than the more riskier and ethically challenged embryonic stem cells.

"ClimateGate" Distilled

I’ve saved a boatload of links about the whole Climate Research Unit e-mail and document leak, but today I came across an article by the aptly-named author Christopher Booker that distills the issue down to 3 salient points.

There are three threads in particular in the leaked documents which have sent a shock wave through informed observers across the world. Perhaps the most obvious, as lucidly put together by Willis Eschenbach (see McIntyre’s blog Climate Audit and Anthony Watt’s blog Watts Up With That ), is the highly disturbing series of emails which show how Dr Jones and his colleagues have for years been discussing the devious tactics whereby they could avoid releasing their data to outsiders under freedom of information laws.

They have come up with every possible excuse for concealing the background data on which their findings and temperature records were based.

Read the rest of this entry

"Adult Stem Cells Saved My Life"

That’s the title of a new campaign by the Family Research Council, trying to get the word out on how so many diseases and conditions (>70) are already being treated successfully with adult stem cells.

Currently the most common and effective treatments using stem cells are various forms of cancers and anemias, he said, though adult stem cells have also repaired heart attack damage, treated leukemias, lymphomas, spinal cord injuries and helped patients with multiple sclerosis and juvenile diabetes. 

When asked about the embryonic stem cell research debate, [David] Prentice [Ph.D., former professor at Indiana State University] noted, “No human beings have even been injected yet” in embryonic stem cell research. Published science, however, has verified the successful treatments of thousands of patients using adult stem cells.

“Lets focus on helping the patients, and helping them now,” Prentice said. “We’re not even talking about embryonic stem cell research. It’s not helping anybody. It’s not even helping the lab rats.”

No human has been injected because of all the complications with embryonic stem cells, including cancer.  In the meantime, adult stem cells, without carrying the ethical and moral baggage, continue to work successfully.  And with new methods being discovered that make adult stem cells as flexible as embryonic, there is absolutely no need to even go down the embryonic path.

You can visit the campaign’s website here.

Shire Network News #169: Ian Plimer

Shire Network News #169 has been released. The feature interview is with Professor Ian Plimer, author of "Heaven and Earth: Global Warming, the Missing Science". Click here for the show notes, links, and ways to listen to the show; directly from the web site, by downloading the mp3 file, or by subscribing with your podcatcher of choice.

Below is the text of my commentary.


Hi, this is Doug Payton for Shire Network News, asking you to "Consider This!"

This is a tale of two countries.  Both have what they call "freedom of religion".  But one imprisons people for converting to a religion that is not the official one.  The other does not. 

Now tell me, which country would you believe if it told you something?  OK, one data point does not a trend make.  Fair enough, then, let’s continue.

Clearly, simply writing something down on paper does not necessarily mean that a country will abide by those things written.  Let’s take a look at a recent event by the country that has freedom of religion but doesn’t, and see the manner in which it practices it.

Two women were arrested on March 5th and later "convicted" of converting to … well, that would be telling, wouldn’t it?  Let’s just say, converting to "a non-approved religion", and we’ll let your imagination get to work.  Into the slammer with them.  [I’m sorry, but I know I’m going to mangle their names.]  Maryam Rustampoor, 27, and Marzieh Amirizadeh, 30, were tried on August 9th and told to recant their faith, which they did not.  Back to the slammer, this time with a death penalty on their heads for daring to practice "freedom" of religion.  Oh, and by the way; medical attention for these young ladies?  Not gonna’ happen.  Injury, meet insult.

The other country?  Well, let’s just say that nobody gets sent to prison for simply believing.  Sometimes doing based on believing can land you in hot water, but just believing?  Well, not even the guys at Gitmo, not even the ones who were shooting, and then released to shoot again, were incarcerated for believing.

Oops, I think I slipped up there a bit.  Well, just pretend I still have you pondering about that particular country, just for a bit.

Now, let me ask you; who comes to the defense of these poor women, still in the hoosegow, awaiting their sentence, for believing?  Not some astroturf organization trying to boost an overall image of their religion, but a group dealing specifically with Christian persecution worldwide.  The web page of International Christian Concern lists place after place where Christians are not the most welcome folks, and indeed this incident is currently mentioned on the front page.  They’re not drumming up feigned offense at perceived slights.  Bodies rotting in slums, rape, murder, physical assault; all for believing

The countries mentioned in the current articles on the front page include Somalia, India, Cuba, Egypt, Pakistan, Burma, Iraq, and one of our mystery countries, Iran.  Are you catching a trend here?  Most of these are Islamic countries with the occasional Hindu and officially atheist country thrown in. 

But Iran gets the Oscar this week for Best Persecution in an Official Capacity for sentencing to death two young women for believing.  For them, there will be no Brian De Palma movie made.  (That broad brush is reserved for the military.)  The United Nations will not pass a resolution on their behalf.  (That remedy is reserved for when Israel so much as blinks.)  The media will not report on them.  (They have better things to do. Michelle Obama’s outfits must be investigated.)  No, Iran gets a pass because Iran knows the world, and so far, the world is ignoring these potential martyrs.

And by the way, these are martyrs; people who could die solely because of what they believe.  If you go on a shooting rampage and get killed in the process, or if you get captured and sent to the Guantanamo Hilton, with 3 squares a day and your every religious requirement fulfilled, buddy, you ain’t a martyr.  I don’t think that word means what you think it means.

And finally, the other mystery country is … well, it’s any of the many countries in this world that was founded on New Testament and/or Old Testament principles — that old-time Judeo-Christian ethic — in which Western civilization is steeped.  Now, none of them are perfect because, so far, they’ve been run by imperfect humans.  But people don’t get incarcerated simply for believing, no matter the religion they’re coming from or going to.  So if you think that one culture and its religious foundation is just as good as any other, and if you think that one country’s word is as good as the other, well then I think you need to take just a bit more time to Consider This.

Not Enough Stem Cell Lines? Blame Bush!

Former President George W. Bush walked a fine line between science and morality/ethics when he decided that existing embryonic stem cell lines, at the time, would be the only ones available for Federal grants.  Federal money would not be available to any new lines.

Contrary to some misinformed, partisan critics, he did not ban embryonic stem cell research.  Companies using private money were not restricted in any way.   Bush simply said that Federal money would be given out in what he believed was as moral and ethical a way as could be done at the time. 

The LA Times reported this week that a Stanford University study was done to determine the extent of this restriction.  The results show that the loudly-complaining scientists have put even tighter restrictions on themselves, making their protests disingenuous.

Read the rest of this entry

Paging Montgomery Scott

This is just too cool not to make mention of.

Oxford scientists have created a transparent form of aluminium by bombarding the metal with the world’s most powerful soft X-ray laser. ‘Transparent aluminium’ previously only existed in science fiction, featuring in the movie Star Trek IV, but the real material is an exotic new state of matter with implications for planetary science and nuclear fusion.

It was Scotty who gave the molecular formula for the fictional "transparent aluminum" to a present-day Plexiglas guy in the movie.  It includes my favorite line to say to my laptop when it seems to be seized up.  Scotty, before using the "quaint" keyboard, attempts to get the attention of the Macintosh in front of him by speaking into the mouse, "Hello, computah", in his classic Scottish brogue. 

Stem Cell Research "Unexplored"?

The Obama administration has finalized its rules regarding embryonic stem cell research.

The new rules, which go into effect on Tuesday, follow President Barack Obama’s March 9 executive order lifting a ban on embryonic stem cell research, an order that went into effect under his predecessor, George W. Bush.

They allow funding for research using human embryonic stem cells created by in-vitro fertilization (IVF) for reproductive purposes and no longer needed, in a departure from the Bush administration’s policy.

Not surprising.  We’ve known this was coming.  What I do find unbelievable is that the administration is still misrepresenting the debate, making it sound like Bush kept all this scientific knowledge away from us.

Bush barred federal funding from supporting work on new lines of stem cells derived from human embryos in 2001, allowing research only on a small number of embryonic stem cell lines that existed at the time.

Using human embryos for scientific research, which often involves their destruction, crossed a moral barrier and urged scientists to consider alternatives, the former president argued.

In reversing the ban, the Obama administration argued that the promise of medical breakthroughs through stem cell research could not go unexplored.

Unexplored?  Adult stem cells have been bringing us these breakthroughs for years, whaddya’ mean "unexplored"?  Adult stem cells have been coaxed into what amount to embryonic cells.  Unexplored? 

Obama wanted to restore science to its "rightful place".  I’d suggest he restore truth to it first.

Obama Displays His Value System

President Obama, demonstrating another example of what my brother-in-law Jim called an "incomplete life ethic", rescinded Bush’s executive order, reversing the ban on most federal funding of embryonic stem cell research.  Bush’s restrictions were informed by his moral beliefs, but Obama will have none of that.

Aides to Obama told reporters in a phone conference Sunday that the new administration intends to be led by a “responsible practice of science and evidence instead of dogma.” Harold Varmus of the president’s Council of Advisors on Science and Technology said, “We view what happened with stem cell research in the last administration as one manifestation of failure to think carefully about how federal support of science and the use of scientific advice occurs.”

He once said that determining when a baby gets human rights was "above my pay grade".  Apparently, deciding when to destroy them isn’t. 

This, then, is apparently the "rightful place" that he promised to restore science to.  It doesn’t sound like morals and ethics are part of the equation anymore. 

Ryan Anderson, writing in the Weekly Standard, brings this point home (as well as noting a "big lie" that Obama continues to perpetuate).

During the ceremony this morning, Obama announced that by signing this executive order "we will lift the ban on federal funding for promising embryonic stem cell research." Of course there never was a ban on federal funding for embryonic stem-cell research. President Bush was, in fact, the first president in history to fund embryonic stem cell research. The compromise Bush reached, however, put restrictions in place that prevented the further destruction of human embryos. It is these restrictions protecting human life that Obama has lifted.

Anderson notes that, while Obama did appeal to "moral values", he set up a straw man that he could easily knock down and brush aside, supposedly taking the issue off the table.  Anderson’s article covers this and a number of other objections that Obama’s decision simply ignores.  Read the whole thing.

The Washington Post headlined their article, "Obama Aims to Shield Science From Politics".  It not only touches on the signing of the EO, but notes how this value system will affect us going forward.  A memorandum was issued along with this signing.

The memorandum will ensure that "people who are appointed to federal positions in science have strong credentials and that the vetting process for evaluating scientific information doesn’t lead to any undermining of the scientific opinion," he said.

That is to say, Obama wishes to shield science from similar ethical concerns, or indeed any debate, during his administration.  Heck, his spokesmen injected politics into the debate by trash-talking "the last administration as one  manifestation of failure to think carefully."  One wonders how the WaPo headline writer actually came up with that summary of the story.

And finally, Scott Ott satirizes this whole situation, such that it can be, with this:

As he signs an executive order Monday lifting limits on federal funding for embryonic stem cell research, President Barack Obama said he intends to make the wealthiest Americans “bear their fair share of the burden.”

Following through on his inaugural promise “to restore science to its rightful place, and wield technology’s wonders to raise health care’s quality and lower its cost“, the president will order the National Institutes of Health to extract stem cells from embryos whose parents earn more than $250,000 per year, and to inject them into “the sick and crippled middle class.”

“Let me be perfectly clear,” Mr. Obama said, “if your family earns less than $250,000 per year, the federal government will not harvest one single stem cell from your embryos…not one single cell. In fact, for 95 percent of working families, my stem cell plan contains nothing but miraculous healing. That’s right, the cures are on the way.”

Again, read the whole thing, and get a good chuckle.

After President Obama’s inaugural speech, when he said, "We will restore science to its rightful place", I wondered aloud (as did others, see that post’s comments) if this had anything to do with his stance on embryonic stem cell research.  Well, it looks like we’ll find out soon enough.

A new way has been found to create stem cells like embryonic ones.

Scientists have developed what appears to be a safer way to create a promising alternative to embryonic stem cells, boosting hopes that such cells could sidestep the moral and political quagmire that has hindered the development of a new generation of cures.

The researchers produced the cells by using strands of genetic material, instead of potentially dangerous genetically engineered viruses, to coax skin cells into a state that appears biologically identical to embryonic stem cells.

"It’s a leap forward in the safe application of these cells," said Andras Nagy of Mount Sinai Hospital in Toronto, who helped lead the international team of researchers that described the work in two papers being published online today by the journal Nature. "We expect this to have a massive impact on this field."

Click here to see all my posts on this issue, and how many alternatives to embryonic stem cells there are (include the hundreds of successful uses for adult stem cells).  All of these methods sidestep completely the ethical question surrounding the use of embryos.  You’d get no hollering from religious conservatives over the possible use of embryonic stem cells as an incentive for, or at least a slight guilt relief from, having an abortion.  That question goes right out the window.

But the scientific and the religious communities hold their breath.

In addition to the scientific implications, the work comes at a politically sensitive moment. Scientists are anxiously waiting for President Obama to follow through on his promise to lift restrictions on federal funding for research on human embryonic stem cells. Critics of such a move immediately pointed to the work as the latest evidence that the alternative cells make such research unnecessary.

"Stem cell research that requires destroying embryos is going the way of the Model T," Richard M. Doerflinger of the U.S. Conference of Catholic Bishops said. "No administration that values science and medical progress over politics will want to divert funds now toward that increasingly obsolete and needlessly divisive approach."

We will see soon enough where Obama thinks that science’s rightful place is.

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